Gwen

Gwen Buchan, 62, who has terminal breast cancer, said capivasertib would allow her to see her son's wedding and gave her "hope".

"Thanks to the trial and the licensing of capivasertib, when used alongside a standard hormonal therapy, patients like Gwen now have the potential to receive a very significant extension in their lifespan and improved quality of life."

There were also peformances from stars including Benson Boone, Gwen Stefani and another award-winner, Janet Jackson.

Other performances on the night saw Gloria Estefan celebrate the legacy of Latin music by doing the Conga, and Gwen Stefani celebrate her noughties hits.

A fan who lives in Orkney, Gwen, told us she had first come across Kneecap "by accident" when her sister told her about the band's now Bafta-winning film.