allele frequency

Notably, an ancestry-biased mRNA isoform of SPSB2, likely driven by cross-population allele frequency differences in rs11064437, was found to be unannotated in canonical gene annotation.

Chinese government researchers contributed the data of 2,143 Uighurs to the Allele Frequency Database, an online search platform run by Dr. Kidd that was partly funded by the United States Department of Justice until last year.

The SNP calling were performed by SAMtools mpileup package69, and SNPs with minor allele frequency lower than 5% were excluded from further analyses.

The excel file incudes: gene, accession number, chromosome coordinates, nucleotide change, amino-acidic change, allele frequency, predicted antigenic peptide and number of different epitopes generated.

Results are stratified by minor allele frequency, and bars indicate the 95% confidence interval for the difference from a two-sided t-test.