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I asked Yoshida if the parallels between ARR and Endwalker were a happy accident or something meticulously planned over these last 10 years.

Screening usually entails a roughly $150 blood test called the aldosterone-to-renin ratio, or ARR.

A positive ARR can be followed by additional tests to confirm the diagnosis and determine whether surgery is an option.

Recent U.S. studies found ARR screening rates for high-risk patients ranging from 1.3 percent in an urban health system to 3.3 percent at an academic medical center.