autosome

The team zeroed in on differences in the ratio of DNA inherited on their X chromosomes compared with the 22 chromosomes that do not determine sex, the so-called autosomes.

A more serious problem arises because the mathematical transformation affects the quantitative comparison between different enrichment profiles by ratio calculations—e.g., when comparing males and females or X chromosomes and autosomes.

The lower plot reports the ratio between X and autosomes.

Divergence was more uniformly distributed along the Z chromosome and did not show the distinct islands of divergence characterizing most autosomes; the Z chromosome contained approximately 35% of all fixed sites in the genome.

Furthermore, the team determined that Papuans have more Denisovan DNA on their autosomes, inherited equally often from both parents, than on their X chromosomes, inherited twice as often from the mother.