BBB

“The BBB will increase by orders of magnitude the scope, scale and speed of removing illegal and criminal aliens from the United States,” Miller posted last week.

"I think Wilders is betraying the Netherlands," said deputy Prime Minister Mona Keijzer from the BBB.

"Lack of an authentic human BBB model has been a major hurdle in studying neurological diseases," says lead corresponding author Ziyuan Guo, PhD, "Our breakthrough involves the generation of human BBB organoids from human pluripotent stem cells, mimicking human neurovascular development to produce a faithful representation of the barrier in growing, functioning brain tissue. This is an important advance because animal models we currently use in research do not accurately reflect human brain development and BBB functionality."

"Now, through stem cell bioengineering, we have developed an innovative platform based on human stem cells that allows us to study the intricate mechanisms governing BBB function and dysfunction. This provides unprecedented opportunities for drug discovery and therapeutic intervention," Guo says.

The research team calls their new model "BBB assembloids."