C.difficile

FMT has a 90% cure rate for C. difficile infection.

"We found reduced vancomycin susceptibility in C. difficile was associated with lower 30-day sustained clinical response and lower 14-day initial cure rates in the studied patient cohort," said Gonzales-Luna.

The fight against C diff takes its toll internally, including a significant disruption of gut microbiota, usually by broad-spectrum antibiotics, leading to loss of colonization resistance to C difficile.

Recurrent C. difficile infections occur after suppressive antibiotic treatments that knock out almost all of the normal gut flora.

Now microbiome experts at the University of Alabama at Birmingham have taken that 2021 study, and a similar study for children who had C. difficile infections, a step further.