coenzyme A

noun

Biochemistry.

a coenzyme, composed of a phosphorylated derivative of pantothenic acid linked to adenylic acid, that participates in the transfer of acyl groups in fatty acid metabolism and amino acid metabolism. CoA

coenzyme A

noun

CoA.��a constituent of biological cells that functions as the agent of acylation in metabolic reactions

coenzyme A

A coenzyme that consists of a nucleotide linked to pantothenic acid (part of the vitamin B complex), is present in all living cells, and functions as an acyl group carrier. Coenzyme A is necessary for fatty acid synthesis and oxidation, pyruvate oxidation, and other acetylation reactions. In cellular respiration, each of two acetyl groups derived from the original glucose molecule attaches itself to coenzyme A as acetyl coenzyme A and then enters the Krebs cycle.

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Word History and Origins

Origin of coenzyme A¹

First recorded in 1935–40

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Example Sentences

Examples have not been reviewed.

Once taken into cells, it is converted into a molecule called coenzyme A, which can then be used in lots of metabolic pathways.

From

Usually, it becomes linked to the molecule coenzyme A to form methylmalonyl-CoA, and is converted to succinyl-CoA in a reaction that involves vitamin B12 as a cofactor.

From

He developed a new method of synthesizing nucleotides, and achieved international recognition for synthesizing coenzyme A, which is involved in converting fats to energy.

From

He found coenzyme A which is a nucleotide containing phosphoric acid.

From

coenzyme coenzyme Q

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