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View synonyms for

mutation

[myoo-tey-shuhn]

noun

  1. Biology.

    1. Also called break.a sudden departure from the parent type in one or more heritable characteristics, caused by a change in a gene or a chromosome.

    2. Also called sport.an individual, species, or the like, resulting from such a departure.

  2. the act or process of changing.

  3. a change or alteration, as in form or nature.

  4. Phonetics.umlaut.

  5. Linguistics.(in Celtic languages) syntactically determined morphophonemic phenomena that affect initial sounds of words.



mutation

/ ːˈٱɪʃə /

noun

  1. the act or process of mutating; change; alteration

  2. a change or alteration

  3. a change in the chromosomes or genes of a cell. When this change occurs in the gametes the structure and development of the resultant offspring may be affected See also inversion

  4. another word for mutant

  5. a physical characteristic of an individual resulting from this type of chromosomal change

  6. phonetics

    1. (in Germanic languages) another name for umlaut

    2. (in Celtic languages) a phonetic change in certain initial consonants caused by a preceding word

“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

mutation

  1. A change in the structure of the genes or chromosomes of an organism. Mutations occurring in the reproductive cells, such as an egg or sperm, can be passed from one generation to the next. Most mutations occur in junk DNA and have no discernible effects on the survivability of an organism. Of the remaining mutations, the majority have harmful effects, while a minority can increase an organism's ability to survive. A mutation that benefits a species may evolve by means of natural selection into a trait shared by some or all members of the species.

  2. See Note at sickle cell anemia

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Other Word Forms

  • mutational adjective
  • mutationally adverb
  • nonmutational adjective
  • nonmutationally adverb
  • unmutational adjective
  • ˈٲپDzԲ adjective
  • ˈٲپDzԲly adverb
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Word History and Origins

Origin of mutation1

First recorded in 1325–75; Middle English mutacio(u)n, from Latin ūپDz- (stem of ūپō ) “a changing”; mutate, -ion
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Example Sentences

Examples have not been reviewed.

The 11-month-old has a mutation of the PPFIBP1 gene which means he is blind, has frequent seizures and is unlikely to ever walk or talk.

From

The researchers think it is possible that the DNA mutation in the gene could cause other changes in these parts of the body linked to health conditions or temperament.

From

Cancer Research UK estimates about seven in 10 women with changes in these genes will develop breast cancer, compared to about one in seven women without these mutations.

From

But these marriages do face a higher risk of a harmful genetic mutation being passed down through the family.

From

A switch from glutamine to leucinein resulting from just one mutation could switch the virus from being able to easily bind to avian, or bird, receptors to favouring human receptors in the respiratory tract.

From

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mutatemutations