South Tyneside

Trial participant Carol Robson, from Jarrow in South Tyneside, says the worst part of living with the disease is the pain, but if the research helps ease suffering "that would be wonderful".

Bottle of Notes, was installed in the same year, having been made by steelworkers in Hebburn, South Tyneside, as part of plans to regenerate the region.

The bass player at the time was Pete Zulu, who left the band in 1985 and now runs the Black Horse pub in Boldon, South Tyneside, with wife Sarah Reid.

South Tyneside, another Labour-run council, said the plans were “wholly unrealistic”, while the independent-run council in Central Bedfordshire, said the area would be left “absolutely swamped with growth that the infrastructure just can not support”.

About 60,000 runners have signed up to the half marathon which starts in Newcastle, heads through Gateshead, South Tyneside and finishes in South Shields.